Performance comparisons between clustering models for reconstructing NGS results from technical replicates

To improve the performance of individual DNA sequencing results, researchers often use replicates from the same individual and various statistical clustering models to reconstruct a high-performance callset. Here, three technical replicates of genome NA12878 were considered and five model types were...

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Bibliographic Details
Main Authors: Yue Zhai, Claire Bardel, Maxime Vallée, Jean Iwaz, Pascal Roy
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1148147/full