Dual Role of Thrombospondin-1 in Flow-Induced Remodeling

Dual Role of Thrombospondin-1 in Flow-Induced Remodeling

(1) Background: Chronic increases in blood flow, as in cardiovascular diseases, induce outward arterial remodeling. Thrombospondin-1 (TSP-1) is known to interact with matrix proteins and immune cell-surface receptors, but its contribution to flow-mediated remodeling in the microcirculation remains u...

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Bibliographic Details
Main Authors: Céline Grenier, Antoine Caillon, Mathilde Munier, Linda Grimaud, Tristan Champin, Bertrand Toutain, Céline Fassot, Olivier Blanc-Brude, Laurent Loufrani
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
thrombospondin-1
blood flow
remodeling
resistance arteries
immune cells
Online Access:https://www.mdpi.com/1422-0067/22/21/12086

Internet

https://www.mdpi.com/1422-0067/22/21/12086

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