Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis

Abstract A successful DNA‐encoded library (DEL) will consist of diverse skeletons and cover chemical space as comprehensive as possible to fully realize its potential in drug discovery and chemical biology. However, the lack of versatile on‐DNA arylation methods for phenols that are less nucleophili...

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Bibliographic Details
Main Authors: Hongtao Xu, Tingting Tan, Yiyuan Zhang, Yan Wang, Kangyin Pan, Ying Yao, Shuning Zhang, Yuang Gu, Wanting Chen, Jie Li, Hewei Dong, Yu Meng, Peixiang Ma, Wei Hou, Guang Yang
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202202790