The tumor suppressor gene <it>TRC8/RNF139 </it>is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma

<p>Abstract</p> <p>Background</p> <p><it>RNF139/TRC8 </it>is a potential tumor suppressor gene with similarity to PTCH, a tumor suppressor implicated in basal cell carcinomas and glioblastomas. <it>TRC8 </it>has the potential to act in a novel re...

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Bibliographic Details
Main Authors: Fiorio Patrizia, Gregorio Andrea, Gambini Claudio, Drabkin Harry A, Beri Silvana, Gimelli Stefania, Zuffardi Orsetta, Gemmill Robert M, Giorda Roberto, Gimelli Giorgio
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/52