Purinergic inhibitory regulation of esophageal smooth muscle is mediated by P2Y receptors and ATP-dependent potassium channels in rats

Abstract Purines such as ATP are regulatory transmitters in motility of the gastrointestinal tract. The aims of this study were to propose functional roles of purinergic regulation of esophageal motility. An isolated segment of the rat esophagus was placed in an organ bath, and mechanical responses...

Full description

Bibliographic Details
Main Authors: Takahiko Shiina, Yuji Suzuki, Kazuhiro Horii, Tomoya Sawamura, Natsufu Yuki, Yuuki Horii, Yasutake Shimizu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Physiological Sciences
Subjects:
Online Access:https://doi.org/10.1186/s12576-024-00916-5