Practical and analytical considerations when performing interim analyses in diagnostic test accuracy studies

Abstract Interim analysis is a common methodology in randomised clinical trials but has received less attention in studies of diagnostic test accuracy. In such studies, early termination for futility may be beneficial if early evidence indicates that a diagnostic test is unlikely to achieve a clinic...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Susannah Fleming, Lazaro Mwandigha, Thomas R. Fanshawe
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2024-08-01
Schriftenreihe:Diagnostic and Prognostic Research
Schlagworte:
Online Zugang:https://doi.org/10.1186/s41512-024-00174-4