Single-cell transcriptome reveals Staphylococcus aureus modulating fibroblast differentiation in the bone-implant interface

Single-cell transcriptome reveals Staphylococcus aureus modulating fibroblast differentiation in the bone-implant interface

Abstract Background This study aimed to delineate the cell heterogeneity in the bone-implant interface and investigate the fibroblast responses to implant-associated S. aureus infection. Methods Single-cell RNA sequencing of human periprosthetic tissues from patients with periprosthetic joint infect...

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Bibliographic Details
Main Authors: Jinlong Yu, Boyong Wang, Feiyang Zhang, Zun Ren, Feng Jiang, Musha Hamushan, Mingzhang Li, Geyong Guo, Hao Shen
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Molecular Medicine
Subjects:
Staphylococcus aureus
scRNA-seq
Fibroblast
Implant-associated infection
Online Access:https://doi.org/10.1186/s10020-023-00632-7

Internet

https://doi.org/10.1186/s10020-023-00632-7

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