Anticancer effects of ikarugamycin and astemizole identified in a screen for stimulators of cellular immune responses

Background Most immunotherapies approved for clinical use rely on the use of recombinant proteins and cell-based approaches, rendering their manufacturing expensive and logistics onerous. The identification of novel small molecule immunotherapeutic agents might overcome such limitations.Method For i...

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Bibliographic Details
Main Authors: Hui Chen, Shuai Zhang, Peng Liu, Yumei Li, Wei Xie, Yang Jin, Laurence Zitvogel, Hui Pan, Guido Kroemer, Oliver Kepp, Ai-Ling Tian, Liwei Zhao, Sijing Li, Misha Mao, Mengfei Guo, Jonathan G Pol
Format: Article
Language:English
Published: BMJ Publishing Group 2023-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/7/e006785.full