Intravenous injection of adult human bone marrow mesenchymal stromal cells attenuates spinal cord ischemia/reperfusion injury in a murine aortic arch crossclamping modelCentral MessagePerspective

Intravenous injection of adult human bone marrow mesenchymal stromal cells attenuates spinal cord ischemia/reperfusion injury in a murine aortic arch crossclamping modelCentral MessagePerspective

Objective: We sought to investigate the efficacy of human bone marrow mesenchymal stem/stromal cell (hBM-MSC) in a murine spinal cord ischemia/reperfusion (SCIR) model. Methods: C57BL/6J mice were subjected to SCIR by crossclamping the aortic arch and left subclavian artery for 5.5 minutes. Two hour...

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Bibliographic Details
Main Authors: Hidekazu Nakai, MD, Yasuyuki Fujita, MD, PhD, Satoru Masuda, MT, Miki Komatsu, MT, Ayumi Tani, MT, Yutaka Okita, MD, PhD, Kenji Okada, MD, PhD, Atsuhiko Kawamoto, MD, PhD
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:JTCVS Open
Subjects:
paraplegia
spinal cord ischemia
spinal cord reperfusion injury
human bone marrow mesenchymal stromal cells
thoracic aortic surgery
Online Access:http://www.sciencedirect.com/science/article/pii/S2666273621001571

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http://www.sciencedirect.com/science/article/pii/S2666273621001571

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