Asparaginase: an old drug with new questions

The long-term outcome of acute lymphoblastic leukemia has improved dramatically due to the development of more effective treatment strategies. L-asparaginase (ASNase) is one of the main drugs used and causes death of leukemic cells by systematically depleting the non-essential amino acid asparagine....

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Bibliographic Details
Main Authors: Daiane Keller Cecconello, Mariana Rodrigues de Magalhães, Isabel Cristina Ribas Werlang, Maria Lucia de Martino Lee, Mariana Bohns Michalowski, Liane Esteves Daudt
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Hematology, Transfusion and Cell Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137919301427