Co-loaded lapatinib/PAB by ferritin nanoparticles eliminated ECM-detached cluster cells via modulating EGFR in triple-negative breast cancer

Co-loaded lapatinib/PAB by ferritin nanoparticles eliminated ECM-detached cluster cells via modulating EGFR in triple-negative breast cancer

Abstract Cancer stem cell (CSC) cluster of triple-negative breast cancer (TNBC) is suggested to be responsible for therapy resistance, metastatic process and cancer recurrence, yet the sensitivity of CSC clusters of TNBC to ferroptosis remains elusive in a great measure. Current research revealed th...

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Bibliographic Details
Main Authors: Xinghan Wu, Huan Sheng, Liping Zhao, Mingxia Jiang, Han Lou, Yue Miao, Ni Cheng, Weifen Zhang, Dejun Ding, Wentong Li
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05007-0

Internet

https://doi.org/10.1038/s41419-022-05007-0

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