CART Immunotherapy: Development, Success, and Translation to Malignant Gliomas and Other Solid Tumors

T cell chimeric antigen receptor (CAR) technology has allowed for the introduction of a high degree of tumor selectivity into adoptive cell transfer therapies. Evolution of this technology has produced a robust antitumor immunotherapeutic strategy that has resulted in dramatic outcomes in liquid can...

Full description

Bibliographic Details
Main Authors: Anna C. Filley, Mario Henriquez, Mahua Dey
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00453/full