A Short History of Topoisomerases at Actelion Pharmaceuticals

The discovery of novel antibacterials devoid of cross resistance is of utmost importance. At the same time, biological pathways and processes suitable to be targeted are limited. At Actelion Pharmaceuticals we decided to work on novel bacterial topoisomerase inhibitors (NBTI) to discover new antibi...

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Bibliographic Details
Main Author: Cornelia Zumbrunn
Format: Article
Language:deu
Published: Swiss Chemical Society 2022-08-01
Series:CHIMIA
Subjects:
Online Access:https://chimia.ch/chimia/article/view/6076