Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors
Acetylcholinesterase (AChE) is one of the classical targets in the treatment of Alzheimer’s disease (AD). Inhibition of AChE slows down the hydrolysis of acetycholine and increases choline levels, improving the cognitive function. The achieved success of plant-based natural drugs acting as AChE inhi...
Main Authors: | Mariyana Atanasova, Ivan Dimitrov, Stefan Ivanov, Borislav Georgiev, Strahil Berkov, Dimitrina Zheleva-Dimitrova, Irini Doytchinova |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-05-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/27/10/3139 |
Similar Items
-
Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening
by: Georgi Stavrakov, et al.
Published: (2021-04-01) -
In Silico Screening of Cinnamon (Cinnamomum burmannii) Bioactive Compounds as Acetylcholinesterase Inhibitors
by: Zatta Yumni Ihdhar Syarafina, et al.
Published: (2022-03-01) -
Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors
by: Georgi Stavrakov, et al.
Published: (2020-07-01) -
Inhibition of Acetylcholinesterase by Novel Lupinine Derivatives
by: Igor A. Schepetkin, et al.
Published: (2023-04-01) -
Molecular Docking Study of Caffeic Acid as Acetylcholinesterase Inhibitor
by: Stephanus Satria Wira Waskitha, et al.
Published: (2023-12-01)