Functional analysis of the citrate activator CitO from Enterococcus faecalis implicates a divalent metal in ligand binding

The regulator of citrate metabolism, CitO, from Enterococcus faecalis belongs to the FCD family within the GntR superfamily. In the presence of citrate, CitO binds to cis-acting sequences located upstream of the cit promoters inducing the expression of genes involved in citrate utilization. The quan...

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Bibliographic Details
Main Authors: Victor S. Blancato, Fernando A Pagliai, Christian eMagni, Claudio Fabricio Gonzalez, Graciela L Lorca
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00101/full