SimSpliceEvol: alternative splicing-aware simulation of biological sequence evolution

Abstract Background It is now well established that eukaryotic coding genes have the ability to produce more than one type of transcript thanks to the mechanisms of alternative splicing and alternative transcription. Because of the lack of gold standard real data on alternative splicing, simulated d...

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Bibliographic Details
Main Authors: Esaie Kuitche, Safa Jammali, Aïda Ouangraoua
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3207-5