Copper Chelation via beta-alanine extends lifespan in a C. elegans model of Alzheimer's Disease

Copper Chelation via beta-alanine extends lifespan in a C. elegans model of Alzheimer's Disease

The leading hypothesis for Alzheimer's Disease (AD) has traditionally focused on the aggregation of Amyloid-β into amyloid plaques. However, research has yet to definitively prove the role of the amyloid peptide in the pathology of the disease. Given that all therapeutics targeting amyloid plaq...

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Bibliographic Details
Main Authors: Arnulfo Pulido, Benjamin Hulbert, Hayleigh Giese, Sabrina Kurian, Rebbeca Rozhon, Michael Zambrano, Oscar Diaz, Mariam Abd, Madison Caputo, Daniel S. Kissel, Mallory A. Havens
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Brain Disorders
Subjects:
Alzheimer's disease
Chelation therapy
Reactive oxygen species
C. elegans
Online Access:http://www.sciencedirect.com/science/article/pii/S2666459323000136

Internet

http://www.sciencedirect.com/science/article/pii/S2666459323000136

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