Development of synthetic modulator enabling long-term propagation and neurogenesis of human embryonic stem cell-derived neural progenitor cells

Abstract Neural progenitor cells (NPCs) are essential for in vitro drug screening and cell-based therapies for brain-related disorders, necessitating well-defined and reproducible culture systems. Current strategies employing protein growth factors pose challenges in terms of both reproducibility an...

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Bibliographic Details
Main Authors: Ceheng Liao, Ying Guan, Jihui Zheng, Xue Wang, Meixia Wang, Zhouhai Zhu, Qiyuan Peng, Hong-Hui Wang, Meng Li
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Biological Research
Online Access:https://doi.org/10.1186/s40659-023-00471-0