Leptin favors imbalance of antigen-specific CD4+ T-cells associated with severity of cat allergy

Leptin favors imbalance of antigen-specific CD4+ T-cells associated with severity of cat allergy

IntroductionObesity can complicate IgE-mediated allergic diseases. In the present study, we aimed to investigate the ability of obesity-related concentrations of leptin to modulate the in vitro effector and regulatory Fel d1-specific CD4+ T-cell subsets in patients allergic to cat, considered the th...

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Bibliographic Details
Main Authors: Carolina Vollmer, Aleida Dias, Marisa Sales, Priscila M. Sacramento, Júlio Cesar Silva, Hugo A. A. Oyamada, Ulisses C. Linhares, Sudhir Gupta, Taissa M. Kasahara, Cleonice A. M. Bento
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
leptin
Fel d1
Th2/Th9
Tfh cells
Treg/Tr-1 cells
Tfr cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1290740/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1290740/full

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