Targeting IL-4 and IL-13 Receptors on Eosinophils in CRSwNP Patients: The Clinical Efficacy of Dupilumab

Targeting IL-4 and IL-13 Receptors on Eosinophils in CRSwNP Patients: The Clinical Efficacy of Dupilumab

Chronic rhinosinusitis with nasal polyposis (CRSwNP) is an inflammatory disease linked to type 2 inflammation. Several biologics have demonstrated therapeutic potential for the treatment of this pathology in which IL-4, IL-5 and IL-13 represent the major cytokines involved in the control of eosinoph...

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Bibliographic Details
Main Authors: Giovanna Lucia Piazzetta, Nadia Lobello, Emanuela Chiarella, Alberta Rizzuti, Corrado Pelaia, Girolamo Pelaia, Nicola Lombardo
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Journal of Personalized Medicine
Subjects:
chronic rhinosinusitis
nasal polyps
inflammatory disease
type 2 inflammation
dupilumab
cytokines
Online Access:https://www.mdpi.com/2075-4426/13/9/1404

Internet

https://www.mdpi.com/2075-4426/13/9/1404

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