CB2 Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer’s Disease
Abstract The endocannabinoid CB2 receptor system has been implicated in the neuropathology of Alzheimer’s disease (AD). In order to investigate the impact of the CB2 receptor system on AD pathology, a colony of mice with a deleted CB2 receptor gene, CNR2, was established on a transgenic human mutant...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2013-10-01
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Series: | Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.2119/molmed.2013.00140 |