How vascular smooth muscle cell phenotype switching contributes to vascular disease

How vascular smooth muscle cell phenotype switching contributes to vascular disease

Abstract Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier experiments have found that VSMCs possess high plasticity. Vascular injury stimulates VSMCs to switch into a dedifferentiated type, also known as synthetic VSMCs, with a high migration and proliferation capa...

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Bibliographic Details
Main Authors: Genmao Cao, Xuezhen Xuan, Jie Hu, Ruijing Zhang, Haijiang Jin, Honglin Dong
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Cell Communication and Signaling
Subjects:
Vascular smooth muscle cells
Phenotype switching
Atherosclerosis
Vascular aging
Aortic aneurysm
Online Access:https://doi.org/10.1186/s12964-022-00993-2

Internet

https://doi.org/10.1186/s12964-022-00993-2

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