Construction of the model for predicting prognosis by key genes regulating EGFR-TKI resistance

Construction of the model for predicting prognosis by key genes regulating EGFR-TKI resistance

Background: Previous studies have suggested that patients with lung adenocarcinoma (LUAD) will significantly benefit from epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI). However, many LUAD patients will develop resistance to EGFR-TKI. Thus, our study aims to develop models to...

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Bibliographic Details
Main Authors: Jinke Zhuge, Xiuqing Wang, Jingtai Li, Tongyuan Wang, Hongkang Wang, Mingxing Yang, Wen Dong, Yong Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
drug resistance
EGFR-TKI
LUAD
nomogram
prognosis prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.968376/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.968376/full

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