Novel nanotherapeutics for cancer immunotherapy by albumin nanoparticles functionalized with PD-1 and PD-L1 aptamers

Novel nanotherapeutics for cancer immunotherapy by albumin nanoparticles functionalized with PD-1 and PD-L1 aptamers

Abstract Background PD-1/PD-L1 blockade plays a crucial role in cancer immunotherapy. Exploration of new technologies to further enhance the efficacy of PD-1/PD-L1 blockade is therefore of potential medical importance. Nanotherapeutics can accumulate in tumor tissues due to enhanced permeability and...

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Bibliographic Details
Main Authors: Qiping Jiang, Fengjiao Yao, Yacong An, Xialian Lai, Xundou Li, Zhen Yu, Xian-Da Yang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cancer Nanotechnology
Subjects:
Aptamers
Albumin
Nanoparticles
Immunotherapy
PD-1
PD-L1
Online Access:https://doi.org/10.1186/s12645-023-00239-x

Internet

https://doi.org/10.1186/s12645-023-00239-x

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