Analysis of the Effect of the TRPC4/TRPC5 Blocker, ML204, in Sucrose-Induced Metabolic Imbalance

Analysis of the Effect of the TRPC4/TRPC5 Blocker, ML204, in Sucrose-Induced Metabolic Imbalance

Sugar-induced metabolic imbalances are a major health problem since an excessive consumption of saccharides has been linked to greater obesity rates at a global level. Sucrose, a disaccharide composed of 50% glucose and 50% fructose, is commonly used in the food industry and found in a range of fast...

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Bibliographic Details
Main Authors: Mizael C. Araújo, Suzany H. S. Soczek, Jaqueline P. Pontes, Bruno A. S. Pinto, Lucas M. França, Bruna da Silva Soley, Gabriela S. Santos, Warlison F. de Silva Saminez, Fernanda K. M. Fernandes, João L. do Carmo Lima, Daniele Maria-Ferreira, João F. S. Rodrigues, Nara L. M. Quintão, Valério Monteiro-Neto, Antônio M. A. Paes, Elizabeth S. Fernandes
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceuticals
Subjects:
high sucrose intake
metabolic changes
fat deposition
hepatic steatosis
TRPC4 and TRPC5 channels
Online Access:https://www.mdpi.com/1424-8247/16/8/1100

Internet

https://www.mdpi.com/1424-8247/16/8/1100

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