Nuclear accumulation of host transcripts during Zika Virus Infection.

Nuclear accumulation of host transcripts during Zika Virus Infection.

Zika virus (ZIKV) infects fetal neural progenitor cells (NPCs) causing severe neurodevelopmental disorders in utero. Multiple pathways involved in normal brain development are dysfunctional in infected NPCs but how ZIKV centrally reprograms these pathways remains unknown. Here we show that ZIKV infe...

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Bibliographic Details
Main Authors: Kristoffer E Leon, Mir M Khalid, Ryan A Flynn, Krystal A Fontaine, Thong T Nguyen, G Renuka Kumar, Camille R Simoneau, Sakshi Tomar, David Jimenez-Morales, Mariah Dunlap, Julia Kaye, Priya S Shah, Steven Finkbeiner, Nevan J Krogan, Carolyn Bertozzi, Jan E Carette, Melanie Ott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011070

Internet

https://doi.org/10.1371/journal.ppat.1011070

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