Kinetics of leptin binding to the Q223R leptin receptor.

Studies in human populations and mouse models of disease have linked the common leptin receptor Q223R mutation to obesity, multiple forms of cancer, adverse drug reactions, and susceptibility to enteric and respiratory infections. Contradictory results cast doubt on the phenotypic consequences of th...

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Bibliographic Details
Main Authors: Hans Verkerke, Caitlin Naylor, Lennart Zabeau, Jan Tavernier, William A Petri, Chelsea Marie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990580?pdf=render