Liquid biopsy for detecting epidermal growth factor receptor mutation among patients with non-small cell lung cancer treated with afatinib: a multicenter prospective study

Liquid biopsy for detecting epidermal growth factor receptor mutation among patients with non-small cell lung cancer treated with afatinib: a multicenter prospective study

Abstract Background This study aimed to determine the effectiveness of liquid biopsy in detecting epidermal growth factor receptor (EGFR) mutations at diagnosis, disease progression, and intermediate stages. Methods This prospective, multicenter, observational study included 30 patients with non-sma...

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Bibliographic Details
Main Authors: Hiroaki Fujii, Hideyuki Nagakura, Nobuaki Kobayashi, Sousuke Kubo, Katsushi Tanaka, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Masanori Nishikawa, Kenji Miura, Harumi Koizumi, Yu Ito, Motofumi Tsubakihara, Naoki Miyazawa, Makoto Kudo, Masaharu Shinkai, Takeshi Kaneko
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Cancer
Subjects:
Cell-free deoxyribonucleic acid
Epidermal growth factor receptor
Liquid biopsy
Non-small cell lung cancer
Second-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
Online Access:https://doi.org/10.1186/s12885-022-10135-z

Internet

https://doi.org/10.1186/s12885-022-10135-z

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