Functional identification of microRNA-centered complexes in C. elegans

Abstract microRNAs (miRNAs) are crucial for normal development and physiology. To identify factors that might coordinate with miRNAs to regulate gene expression, we used 2′O-methylated oligonucleotides to precipitate Caenorhabditis elegans let-7, miR-58, and miR-2 miRNAs and the associated proteins....

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Bibliographic Details
Main Authors: Shilpa Hebbar, Ganesh Panzade, Ajay A. Vashisht, James A. Wohlschlegel, Isana Veksler-Lublinsky, Anna Y. Zinovyeva
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10771-2