CD8+ Tumor-Infiltrating T Cells Are Trapped in the Tumor-Dendritic Cell Network

Chemotherapy enhances the antitumor adaptive immune T cell response, but the immunosuppressive tumor environment often dominates, resulting in cancer relapse. Antigen-presenting cells such as tumor-associated macrophages (TAMs) and tumor dendritic cells (TuDCs) are the main protagonists of tumor-inf...

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Bibliographic Details
Main Authors: Alexandre Boissonnas, Fabrice Licata, Lucie Poupel, Sébastien Jacquelin, Luc Fetler, Sophie Krumeich, Clotilde Théry, Sébastian Amigorena, Christophe Combadière
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613801285