Clinical implication of low estrogen receptor (ER-low) expression in breast cancer

Clinical implication of low estrogen receptor (ER-low) expression in breast cancer

Breast cancer is a heterogeneous disease, and the estrogen receptor (ER) remains the most important biomarker in breast oncology. Most guidelines set a positive expression threshold of 1% staining in immunohistochemistry (IHC) to define ER positivity. However, different expression levels may be asso...

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Bibliographic Details
Main Authors: Tomás Reinert, Fanny Cascelli, Cristiano Augusto Andrade de Resende, Aline Coelho Gonçalves, Vania Sanchez Prette Godo, Carlos Henrique Barrios
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
breast cancer
estrogen receptor
endocrine therapy
ESR1
ER low positive
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1015388/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1015388/full

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