Assessing causal relationship between circulating cytokines and age-related neurodegenerative diseases: a bidirectional two-sample Mendelian randomization analysis

Abstract Numerous studies have reported that circulating cytokines (CCs) are linked to age-related neurodegenerative diseases (ANDDs); however, there is a lack of systematic investigation for the causal association. A two-sample bidirectional Mendelian Randomisation (MR) method was utilized to evalu...

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Bibliographic Details
Main Authors: Zihan Yin, Jiao Chen, Manze Xia, Xinyue Zhang, Yaqin Li, Zhenghong Chen, Qiongnan Bao, Wanqi Zhong, Jin Yao, Kexin Wu, Ling Zhao, Fanrong Liang
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39520-9