The individual components of commercial isometamidium do not possess stronger trypanocidal activity than the mixture, nor bypass isometamidium resistance

The four components present in the trypanocidal treatment Samorin, the commercially available formulation of isometamidium, were separated and purified by column chromatography. These compounds as well as the Samorin mixture and the other phenanthridine trypanocide, homidium, were tested on Trypanos...

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Bibliographic Details
Main Authors: Anthonius A. Eze, John Igoli, Alexander I. Gray, Graham G. Skellern, Harry P. De Koning
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320718301830