The role of Raptor in lymphocytes differentiation and function

The role of Raptor in lymphocytes differentiation and function

Raptor, a key component of mTORC1, is required for recruiting substrates to mTORC1 and contributing to its subcellular localization. Raptor has a highly conserved N-terminus domain and seven WD40 repeats, which interact with mTOR and other mTORC1-related proteins. mTORC1 participates in various cell...

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Bibliographic Details
Main Authors: Jianing Tang, Lu Yang, Fei Guan, Heather Miller, Niels Olsen Saraiva Camara, Louisa K. James, Kamel Benlagha, Masato Kubo, Steffen Heegaard, Pamela Lee, Jiahui Lei, Hu Zeng, Chengwei He, Zhimin Zhai, Chaohong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
Raptor
mTORC1
T cell
B cell
immune
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1146628/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1146628/full

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