The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis

The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis

Abstract Background Synovitis-associated pain is mediated by inflammatory factors that may include S100A8/9, which is able to stimulate nociceptive neurons via Toll-like receptor 4. In this study, we investigated the role of S100A9 in pain response during acute synovitis. Methods Acute synovitis was...

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Bibliographic Details
Main Authors: Arjen B. Blom, Martijn H. van den Bosch, Esmeralda N. Blaney Davidson, Johannes Roth, Thomas Vogl, Fons A. van de Loo, Marije Koenders, Peter M. van der Kraan, Edwin J. Geven, Peter L. van Lent
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Arthritis Research & Therapy
Subjects:
Synovitis
Pain
Nociception
Alarmins
S100A8
S100A9
Online Access:http://link.springer.com/article/10.1186/s13075-020-02295-9

Internet

http://link.springer.com/article/10.1186/s13075-020-02295-9

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