Significance of monoclonal antibodies against the conserved epitopes within non-structural protein 3 helicase of hepatitis C virus.

Nonstructural protein 3 (NS3) of hepatitis C virus (HCV), codes for protease and helicase carrying NTPase enzymatic activities, plays a crucial role in viral replication and an ideal target for diagnosis, antiviral therapy and vaccine development. In this study, monoclonal antibodies (mAbs) to NS3 h...

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Bibliographic Details
Main Authors: Yixin Bian, Shuoxian Zhao, Shaomei Zhu, Jinfeng Zeng, Tingting Li, Yongshui Fu, Yuanzhan Wang, Xin Zheng, Ling Zhang, Wenjing Wang, Baocheng Yang, Yuanping Zhou, Jean-Pierre Allain, Chengyao Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3722154?pdf=render