Analysis of an ordered, comprehensive STM mutant library in infectious Borrelia burgdorferi: insights into the genes required for mouse infectivity.

Analysis of an ordered, comprehensive STM mutant library in infectious Borrelia burgdorferi: insights into the genes required for mouse infectivity.

The identification of genes important in the pathogenesis of Lyme disease Borrelia has been hampered by exceedingly low transformation rates in low-passage, infectious organisms. Using the infectious, moderately transformable B. burgdorferi derivative 5A18NP1 and signature-tagged versions of the Him...

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Bibliographic Details
Main Authors: Tao Lin, Lihui Gao, Chuhua Zhang, Evelyn Odeh, Mary B Jacobs, Loïc Coutte, George Chaconas, Mario T Philipp, Steven J Norris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485029?pdf=render

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http://europepmc.org/articles/PMC3485029?pdf=render

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