Generation of Spike-Extracellular Vesicles (S-EVs) as a Tool to Mimic SARS-CoV-2 Interaction with Host Cells

Generation of Spike-Extracellular Vesicles (S-EVs) as a Tool to Mimic SARS-CoV-2 Interaction with Host Cells

Extracellular vesicles (EVs) and viruses share common features: size, structure, biogenesis and uptake. In order to generate EVs expressing the SARS-CoV-2 spike protein on their surface (S-EVs), we collected EVs from SARS-CoV-2 spike expressing human embryonic kidney (HEK-293T) cells by stable trans...

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Bibliographic Details
Main Authors: Roberta Verta, Cristina Grange, Renata Skovronova, Adele Tanzi, Licia Peruzzi, Maria Chiara Deregibus, Giovanni Camussi, Benedetta Bussolati
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
extracellular vesicles
COVID-19
SARS-CoV-2
SARS-CoV-2 spike protein
colchicine
anti-ACE2
Online Access:https://www.mdpi.com/2073-4409/11/1/146

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https://www.mdpi.com/2073-4409/11/1/146

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