Deficient induction response in a Xenopus nucleocytoplasmic hybrid.

Incompatibilities between the nucleus and the cytoplasm of sufficiently distant species result in developmental arrest of hybrid and nucleocytoplasmic hybrid (cybrid) embryos. Several hypotheses have been proposed to explain their lethality, including problems in embryonic genome activation (EGA) an...

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Bibliographic Details
Main Authors: Patrick Narbonne, David E Simpson, John B Gurdon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22131902/?tool=EBI