Microarray expression analysis in idiopathic and LRRK2-associated Parkinson's disease

Microarray expression analysis in idiopathic and LRRK2-associated Parkinson's disease

LRRK2 mutations are the most common genetic cause of Parkinson's disease (PD). We performed a whole-genome RNA profiling of putamen tissue from idiopathic PD (IPD), LRRK2-associated PD (G2019S mutation), neurologically healthy controls and one asymptomatic LRRK2 mutation carrier, by using the G...

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Bibliographic Details
Main Authors: Teresa Botta-Orfila, Eduard Tolosa, Ellen Gelpi, Alex Sànchez-Pla, Maria-José Martí, Francesc Valldeoriola, Manel Fernández, Francesc Carmona, Mario Ezquerra
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Neurobiology of Disease
Subjects:
Parkinson's Disease
LRRK2
Putamen
Gene expression
Microarray
Quantitative real-time PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111003032

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http://www.sciencedirect.com/science/article/pii/S0969996111003032

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