Investigation of the impact of clonal hematopoiesis on severity and pathophysiology of COVID-19 in rhesus macaques

Investigation of the impact of clonal hematopoiesis on severity and pathophysiology of COVID-19 in rhesus macaques

Clinical manifestations of COVID-19 vary widely, ranging from asymptomatic to severe respiratory failure with profound inflammation. Although risk factors for severe illness have been identified, definitive determinants remain elusive. Clonal hematopoiesis (CH), the expansion of hematopoietic stem a...

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Bibliographic Details
Main Authors: Tae-Hoon Shin, Yifan Zhou, Byung-Chul Lee, So Gun Hong, Shayne F. Andrew, Barbara J. Flynn, Matthew Gagne, John-Paul M. Todd, Ian N. Moore, Anthony Cook, Mark G. Lewis, Kathryn E. Foulds, Robert A. Seder, Daniel C. Douek, Mario Roederer, Cynthia E. Dunbar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Veterinary Science
Subjects:
clonal hematopoiesis
COVID-19
SARS-CoV-2
rhesus macaque
aging
hyperinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1182197/full

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https://www.frontiersin.org/articles/10.3389/fvets.2023.1182197/full

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