N-Acetyl-Cysteine-Loaded Biomimetic Nanofibrous Scaffold for Osteogenesis of Induced-Pluripotent-Stem-Cell-Derived Mesenchymal Stem Cells and Bone Regeneration

N-Acetyl-Cysteine-Loaded Biomimetic Nanofibrous Scaffold for Osteogenesis of Induced-Pluripotent-Stem-Cell-Derived Mesenchymal Stem Cells and Bone Regeneration

To regenerate bone tissues, we investigated the osteogenic differentiation of induced-pluripotent-stem-cell-derived mesenchymal stem cells (iPSC-MSCs) and bone regeneration capacities using N-acetyl cysteine (NAC)-loaded biomimetic nanofibers of hydroxyapatite/silk fibroin (HAp/SF). The addition of...

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Bibliographic Details
Main Authors: Xiaolei Li, Feng Xiong, Shuguang Wang, Zhuojun Zhang, Jihang Dai, Hui Chen, Jingcheng Wang, Qiang Wang, Huihua Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
bone tissue engineering
n-acetyl cysteine
HAp/SF nanofibers
drug release
osteogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.767641/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.767641/full

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