The Domino Effect: Nucleosome Dynamics and the Regulation of Base Excision Repair Enzymes

DNA damage is induced by exogenous and endogenous sources, creating a variety of lesions. However, the cellular repair machinery that addresses and corrects this damage must contend with the fact that genomic DNA is sequestered in the nucleoprotein complex of chromatin. As the minimal unit of DNA co...

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Bibliographic Details
Main Authors: Julia C. Cook, Sarah Delaney
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:DNA
Subjects:
Online Access:https://www.mdpi.com/2673-8856/2/4/18