The Domino Effect: Nucleosome Dynamics and the Regulation of Base Excision Repair Enzymes
DNA damage is induced by exogenous and endogenous sources, creating a variety of lesions. However, the cellular repair machinery that addresses and corrects this damage must contend with the fact that genomic DNA is sequestered in the nucleoprotein complex of chromatin. As the minimal unit of DNA co...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
|
Series: | DNA |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-8856/2/4/18 |