NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis

NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis

NKG2D is an activating receptor expressed on the surface of immune cells including subsets of T lymphocytes. NKG2D binds multiple ligands (NKG2DL) whose expression are differentially triggered in a cell type and stress specific manner. The NKG2D-NKG2DL interaction has been involved in autoimmune dis...

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Bibliographic Details
Main Authors: Laurine Legroux, Ana Carmena Moratalla, Cyril Laurent, Gabrielle Deblois, Sandrine L. Verstraeten, Nathalie Arbour
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
T lymphocytes
central nervous system
autoimmune disease
neuroinflammation
NK cell lectin-like receptor subfamily
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00154/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00154/full

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