Emerging Roles of Autophagy and Inflammasome in Ehrlichiosis

Emerging Roles of Autophagy and Inflammasome in Ehrlichiosis

Human monocytic ehrlichiosis (HME) is a potentially life-threatening tick-borne rickettsial disease (TBRD) caused by the obligate intracellular Gram-negative bacteria, Ehrlichia. Fatal HME presents with acute ailments of sepsis and toxic shock-like symptoms that can evolve to multi-organ failure and...

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Bibliographic Details
Main Authors: Tyler R. Tominello, Edson R. A. Oliveira, Shah S. Hussain, Amr Elfert, Jakob Wells, Brandon Golden, Nahed Ismail
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
ehrlichiosis
inflammasome
autophagy
pathogenesis
innate immunity
mechanism
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01011/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01011/full

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