The biological principles and advanced applications of DSB repair in CRISPR-mediated yeast genome editing

To improve the performance of yeast cell factories for industrial production, extensive CRISPR-mediated genome editing systems have been applied by artificially creating double-strand breaks (DSBs) to introduce mutations with the assistance of intracellular DSB repair. Diverse strategies of DSB repa...

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Bibliographic Details
Main Authors: Wenxin Bai, Meilan Huang, Chun Li, Jun Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-12-01
Series:Synthetic and Systems Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X2300073X