Molecular Therapeutic Approaches for Pediatric Acute Myeloid Leukemia

Molecular Therapeutic Approaches for Pediatric Acute Myeloid Leukemia

Approximately two thirds of children with acute myeloid leukemia (AML) are cured with intensive multi-agent chemotherapy. However, primary chemorefractory and relapsed AML remains a significant source of childhood cancer mortality, highlighting the need for new therapies. Further therapy intensifica...

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Bibliographic Details
Main Authors: Sarah K Tasian, Jessica A Pollard, Richard eAplenc
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Oncology
Subjects:
Antibodies, Monoclonal
Clinical Trials as Topic
Signal Transduction
targeted therapy
tyrosine kinase inhibitors
monoclonal antibodies
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00055/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00055/full

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