β1-Integrin blockade prevents podocyte injury in experimental models of minimal change disease

β1-Integrin blockade prevents podocyte injury in experimental models of minimal change disease

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Introduction: Activation of the focal adhesion kinase (FAK) in podocytes is involved in the pathogenesis of minimal change disease (MCD), but the pathway leading to its activation in this disease is unknown. Here, we tested whether podocyte β1 integrin is the upstream modulator of FAK activation and...

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Bibliographic Details
Main Authors: Gabriel Cara-Fuentes, Rakesh Verma, Madhusudan Venkatareddy, Colin Bauer, Federica Piani, Sogut Turkmen Aksoy, Neha Vazzalwar, Gabriela E. Garcia, Mindy Banks, Flor A. Ordoñez, Carmen de Lucas-Collantes, Petter Bjornstad, Juan D. González Rodríguez, Richard J. Johnson, Puneet Garg
Format: Article
Language:Spanish
Published: Elsevier 2024-01-01
Series:Nefrología
Subjects:
Enfermedad de cambios mínimos
Podocito
Integrina β1
Quinasa de adhesión focal
Online Access:http://www.sciencedirect.com/science/article/pii/S0211699522001771

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http://www.sciencedirect.com/science/article/pii/S0211699522001771

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