Proteomics and mathematical modeling of longitudinal CSF differentiates fast versus slow ALS progression

Abstract Objective Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease with a complex etiology that lacks biomarkers predicting disease progression. The objective of this study was to use longitudinal cerebrospinal fluid (CSF) samples to identify biomarkers that distinguish fast progressi...

Full description

Bibliographic Details
Main Authors: Lucas Vu, Krystine Garcia‐Mansfield, Antonio Pompeiano, Jiyan An, Victoria David‐Dirgo, Ritin Sharma, Vinisha Venugopal, Harkeerat Halait, Guido Marcucci, Ya‐Huei Kuo, Lisa Uechi, Russell C. Rockne, Patrick Pirrotte, Robert Bowser
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51890