Long-Acting β2 Adrenergic Receptor Agonist Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesion by Regulating Keratinocyte Proliferation and Apoptosis

Long-Acting β2 Adrenergic Receptor Agonist Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesion by Regulating Keratinocyte Proliferation and Apoptosis

Psoriasis is a chronic inflammatory disease that affects approximately 1%–5% of the population worldwide. Considering frequent relapse, adverse drug reactions, and large costs of treatment, it is urgent to identify new medications for psoriasis. Keratinocytes play an essential role during psoriasis...

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Bibliographic Details
Main Authors: Rui Xu, Shi Feng, Zhou Ao, Yingxiang Chen, Congping Su, Xiuling Feng, Qin Fu, Xiaoyan Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
psoriasis
cAMP
PKA
PDE4 inhibitor
β2 adrenergic receptor agonist
ERK
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.865715/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.865715/full

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